AMRID LABORATORY

innovation against infection

Translational research

Research at AMRID is conducted with tangible outcomes in mind. Our science is for the world, not for the satisfaction of personal curiosities.

Performed by industry leaders

AMRID employs experts from a diverse range of backgrounds, with broad skill sets spanning all facets of the infectious diseases discipline.

STAFF

Professor

Sam Abraham

Founder & Director

Professor

David Jordan

Epidemiologist

Emeritus Professor

David Hampson

Veterinary Microbiologist

Doctor

Rebecca Abraham

Research Fellow

Doctor

Hui San Allison

Research Fellow

Shewli Mukerji

Research Fellow

Doctor

Marin Milotic

Research Fellow

Alec Truswell

Technical Officer

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Josie Mansfield

Research Officer

Doctor

Jasim Uddin

Veterinary Virologist

STUDENTS

Nikki Asuming-Bediako

PhD Candidate

Breanna Knight

PhD Candidate

Soraya Haynes

PhD Candidate

Michaela Burton

PhD Candidate

Ashiqur Rahman

PhD Candidate

ALUMNI

Doctor

Shafi Sahibzada

Australian Centre for Disease Preparedness

Doctor

Tanya Laird

DPIRD,

Western Australia

Doctor

Zheng Zhou Lee

PhD Graduate

Doctor

Shafi Sahibzada

Australian Centre for Disease Preparedness

COLLABORATORS

Adjunct Professor

Marc Stegger

Statens Serum Institut,

Denmark

Abstract

Surveillance of antimicrobial resistance (AMR) is critical to reducing its wide-reaching impact. Its reliance on sample size invites solutions to longstanding constraints regarding scalability. A robotic platform (RASP) was developed for high-throughput AMR surveillance in accordance with internationally recognized standards (CLSI and ISO 20776-1:2019) and validated through a series of experiments.


While adhering to internationally accepted guidelines, RASP was superior in throughput, cost and data resolution when compared with an experienced human technician. Integration of robotics platforms in the microbiology laboratory is a necessary advancement for future One Health AMR endeavours.

Alec Truswell

Dr. Rebecca

Abraham

Featured Article

Robotic Antimicrobial Susceptibility Platform (RASP): a next-generation approach to One Health surveillance of antimicrobial resistance

RASP-AMR

A next generation model for one health surveilLance of antimicrobial resistance

DETECTION

QUANTIFICATION

PHENOTYPIC SUSCEPTIBILITIES

WHOLE GENOME SEQUENCING

PHYLOGENETIC ANALYSIS

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Mass screen on selective agars

Organism specific agar

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Antimicrobial-infused organism specific agar

Determine level of resistance carriage

Enumeration of antimicrobial resistant target organisms (CFU/mL)

Identify antimicrobial resistance phenotype(s)

Select isolates are screened for additional drug resistances

Classify strain and identify gene carriage

Multi-locus sequence typing and detection of specified genes

Trace isolate genetic lineage and evolution

Global comparison to historic isolates to provide epidemiological context

Different Types of Laboratory Flasks

Get in touch

Business Address

Murdoch University

90, South Street Murdoch WA 6150.

Building 240, Level 2, Room 2.047c.


Email Address

s.abraham@murdoch.edu.au


Harry Butler Institute